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D-3263 hydrochloride

CAS No. 1008763-54-9

D-3263 hydrochloride ( D3263 HCl salt; EC D-3263 HCl )

产品货号. M26136 CAS No. 1008763-54-9

D-3263 hydrochloride is enteric-coated, orally bioavailable (transient receptor potential melatonin member 8) TRPM8 agonist.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥915 有现货
10MG ¥1442 有现货
25MG ¥2697 有现货
50MG ¥4528 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    D-3263 hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    D-3263 hydrochloride is enteric-coated, orally bioavailable (transient receptor potential melatonin member 8) TRPM8 agonist.
  • 产品描述
    D-3263 hydrochloride is enteric-coated, orally bioavailable (transient receptor potential melatonin member 8) TRPM8 agonist.(In Vitro):D-3263 hydrochloride binds and activates TRPM8, which may lead to increased entry of calcium and sodium; destruction of calcium and sodium homeostasis; induction of cell death in tumor cells expressing TRPM8. D-3263 hydrochloride may reduce the level of dihydrotestosterone (DHT), which may contribute to its inhibitory effect on prostate cancer and BPH.
  • 同义词
    D3263 HCl salt; EC D-3263 HCl
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    GnRHR
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1008763-54-9
  • 分子量
    410.0
  • 分子式
    C21H32ClN3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cl.COc1ccc2n(C(=O)[C@@H]3C[C@H](C)CC[C@H]3C(C)C)c(=O)n(CCN)c2c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Ezzati M, Carr BR (2015).?"Elagolix, a novel, orally bioavailable GnRH antagonist under investigation for the treatment of endometriosis-related pain".?Womens Health (Lond).?11?(1): 19–28.
产品手册
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